|  | Slime Ward - Fel Ash Experimentation Notes Common · Quest | 1 | | Quest | | Common | | |
|  | Slightly Creased Note Common · Junk | 1 | 1 | Junk | | Common | | |
|  | Slidore's Beacon Common · Quest | 1 | | Quest | | Common | | |
|  | Slice of Carrie's Apple Pie Common · Other | 1 | 1 | Other | | Common | | 30 silver |
|  | Sleeping Robes Uncommon · Cloth · Chest | 10 | | Cloth | Chest | Uncommon | | 94 copper |
|  | Sleepers' Key Common · Quest | 1 | | Quest | | Common | | |
|  | Sleek Bat Pelt Poor · Junk | 1 | | Junk | | Poor | | 12 silver 5 copper |
|  | Slayer's Crest Epic · Miscellaneous · Trinket | 90 | 60 | Miscellaneous | Trinket | Epic | | 9 gold 11 silver 60 copper |
|  | Slatemetal Cutlass Uncommon · Sword · One-Hand | 24 | | Sword | One-Hand | Uncommon | | 24 silver 83 copper |
|  | Slagtree's Lost Tools Common · Quest | 1 | | Quest | | Common | | |
|  | Slab of Carrion Worm Meat Common · Quest | 1 | | Quest | | Common | | |
|  | Skywall Souffle Common · Food & Drink | 15 | 5 | Food & Drink | | Common | Crafted | 1 silver |
|  | Skysilk Wristguards Common · Cloth · Wrist | 10 | | Cloth | Wrist | Common | | 29 copper |
|  | Skylord Plume Common · Quest | 1 | | Quest | | Common | | |
|  | Skybreaker Bulwark Common · Quest | 1 | | Quest | | Common | | |
|  | Skyborne Tabard Common · Miscellaneous · Tabard | 20 | | Miscellaneous | Tabard | Common | | 1 gold 25 silver |
|  | Skullsplitter Tusk Common · Quest | 1 | | Quest | | Common | | |
|  | Skullsplitter Fetish Common · Quest | 1 | | Quest | | Common | | |
|  | Skullsplitter Coin Uncommon · Quest | 1 | | Quest | | Uncommon | | |
|  | Skullspell Orb Uncommon · Miscellaneous · Held In Off-hand | 52 | | Miscellaneous | Held In Off-hand | Uncommon | | 89 silver 82 copper |
|  | Skullbasher Common · Quest | 1 | | Quest | | Common | | |
|  | Skull of the Coldbringer Common · Quest | 1 | | Quest | | Common | | |
|  | Skull of Korrak Common · Quest | 60 | 1 | Quest | | Common | | |
| | Skull of Impending Doom Uncommon · Miscellaneous · Held In Off-hand | 41 | | Miscellaneous | Held In Off-hand | Uncommon | | 56 silver 30 copper |
| | Skull of Horgus Common · Quest | 1 | | Quest | | Common | | |
|  | Skull Wrapping Paper Common · Other | 40 | 40 | Other | | Common | | 12 silver 50 copper |
|  | Skull Ring Uncommon · Miscellaneous · Finger | 25 | | Miscellaneous | Finger | Uncommon | | 12 silver 50 copper |
|  | Skull Key Common · Other | 1 | | Other | | Common | | |
|  | Skull Gift Common · Other | 45 | 35 | Other | | Common | | |
|  | Skulker's Shiv Uncommon · Dagger · One-Hand | 10 | | Dagger | One-Hand | Uncommon | | 1 silver 42 copper |
|  | Skonk's List Common · Quest | 1 | | Quest | | Common | | |
|  | Skittering Blood Common · Quest | 1 | | Quest | | Common | | |
|  | Skinning Knife Common · Miscellaneous · One-Hand | 4 | 1 | Miscellaneous | One-Hand | Common | | 2 copper |
|  | Skin of the Great Sandworm Epic · Quest | 1 | | Quest | | Epic | | |
|  | Skin of Sweet Rum Common · Quest | 1 | | Quest | | Common | | 1 silver 68 copper |
|  | Skin of Shadow Uncommon · Quest | 1 | | Quest | | Uncommon | | |
|  | Skin of Dwarven Stout Common · Food & Drink | 15 | | Food & Drink | | Common | | 30 copper |
|  | Skilled Handling Gloves Uncommon · Cloth · Hands | 46 | | Cloth | Hands | Uncommon | | 33 silver 81 copper |
|  | Skeleton Key Mold Common · Quest | 1 | | Quest | | Common | | |
|  | Skeleton Key Common · Key | 1 | | Key | | Common | | |
|  | Skeleton Finger Common · Quest | 1 | | Quest | | Common | | |
|  | Skeletal Steed Reins Epic · Junk | 60 | 60 | Junk | | Epic | | 25 gold |
| | Skeletal Steed Epic · Junk | 60 | 40 | Junk | | Epic | | |
|  | Skeletal Hitching Post Epic · Junk | 60 | 60 | Junk | | Epic | | |
|  | Skeletal Fragments Common · Quest | 1 | | Quest | | Common | | |
|  | Skeletal Artifact Rare · Other | 1 | 1 | Other | | Rare | | |
|  | Sixth Mosh'aru Tablet Common · Quest | 1 | | Quest | | Common | | |
|  | Six of Wilds Rare · Junk | 1 | | Junk | | Rare | | 1 gold 25 silver |
|  | Six of Warlords Rare · Quest | 1 | | Quest | | Rare | | 1 gold 25 silver |
|  | Six of Portals Rare · Quest | 1 | | Quest | | Rare | | 1 gold 25 silver |
